Publications

Trink Y, Urbach A, Dekel B, Hohenstein P, Goldberger J, Kalisky T. “Characterization of Continuous Transcriptional Heterogeneity in High-Risk Blastemal-Type Wilms’ Tumors Using Unsupervised Machine Learning” Int J Mol Sci. (2023) 24(4):3532. PMID: 36834944

Wineberg Y, Kanter I, Ben-Haim N, Pode-Shakked N, Bucris E, Bar-Lev TH, Oriel S, Reinus H, Yehuda Y, Gershon R, Shukrun R, Bar-Lev DD, Urbach A, Dekel B, Kalisky T. “Characterization of alternative mRNA splicing in cultured cell populations representing progressive stages of human fetal kidney development”.  Scientific Reports (2022) 12(1):19548. PMID: 36380228

Ben-Haim Y, Armon L, Fichtman B, Epshtein I, Spiegel R, Harel A, Urbach A. “Generation and characterization of iPSC lines from two nuclear envelopathy patients with a homozygous nonsense mutation in the TOR1AIP1 gene”. Stem Cell Res (2021);56:102539. PMID: 34560421.

Attali-Padael Y, Armon L, Urbach A. “Apoptosis induction by the stem cell factor LIN28A”. Biol Cell (2021) 113(11):450-457.  PMID: 34437724.

Gross-Carmel I, Armon L, Levy E, Waldman Ben-Asher H, Yaron O, Urbach A. “Human pluripotent stem cell fate regulation by SMARCB1″. Stem Cell Reports (2020) 15(5):1037-1046. PMID: 33125876.

Wineberg Y*, Bar-Lev T*, Futorian A*, Ben-Haim N, Armon L, Ickowicz D, Oriel S, Bucris E, Yehuda Y, Pode-Shakked N, Gilad S, Benjamin S, Hohenstein P, Dekel B#, Urbach A#, Kalisky T#. “Single-cell RNA sequencing reveals mRNA splice isoform switching during kidney development”. JASN (2020) 31(10):2278-2291. PMID: 32651222 *co-first authors # co-last authors

Komarovsky Gulman Nelly, Armon Leah, Urbach A. “Lin28 over-expression delays normal embryonic lung development”. FASEB J (2019) 33(11): 12008-12018. PMID: 31373834.

Robinton DA, Chal J, Lummertz da Rocha E, Han A, Yermalovich AV, Oginuma M, Schlaeger TM, Sousa P, Rodriguez A, Urbach A, Pourquié O, Daley GQ. The Lin28/Let-7 pathway regulates the mammalian caudal body axis elongation program. Dev Cell (2019) 48; 395-406. PMID: 30661985.

Trink A, Kanter I, Pode-Shakked N, Urbach A, Dekel B, Kalisky T. “Geometry of gene expression space of wilms’ tumors from human patients.” Neoplasia (2018) 17;20(8):871-881. PMID: 30029183.

Pleniceanu O, Shukrun R, Omer D, Vax E, Kanter I, Dziedzic K, Pode-Shakked N, Mark-Daniei M, Pri-Chen S, Gnatek Y, Alfandary H, Varda-Bloom N, Bar-Lev DD, Bollag N, Shtainfeld R, Armon L, Urbach A, Kalisky T, Nagler A, Harari-Steinberg O, Arbiser JL, Dekel B. “PPARG is central to the initiation and propagation of human angiomyolipoma, suggesting its potential as a therapeutic target.” EMBO Mol Med. (2017), 9(4):508-530. PMID: 28275008.

Carmel-Gross I, Bollag N, Armon L, Urbach A. ” Lin28 – a stem cells factor with a key role in pediatric tumor formation.” Stem Cell Dev (2016) 1;25(5):367-77. PMID: 26692113.

Halevy T and Urbach A. “Comparing ESC and iPSC—Based Models for Human Genetic Disorders” J. Clin. Med. (2014) 3(4), 1146-1162; PMID: 26237596.

Urbach A, Yermalovich A, Spina CS, Zhu H, Perez-Atayde AR, Shukrun R, Charlton J, Sebire N, Mifsud W, Dekel B, Pritchard-Jones K, Daley GQ. “Lin28 sustains early renal progenitors and induces Wilms tumor”; Genes Dev. (2014) 28(9):971-82. PMID: 24732380.

Zhu H, Shyh-Chang N, Segrè AV, Shinoda G, Shah SP, Einhorn WS, Takeuchi A, Engreitz JM, Hagan JP, Kharas MG, Urbach A, Thornton JE, Triboulet R, Gregory RI; DIAGRAM Consortium; MAGIC Investigators, Altshuler D, Daley GQ. “The Lin28/let-7 axis regulates glucose metabolism”; Cell (2011), 147(1):81-94. PMID: 21962509.

Loh YH, Hartung O, Li H, Guo C, Sahalie JM, Manos PD, Urbach A, Heffner GC, Grskovic M, Vigneault F, Lensch MW, Park IH, Agarwal S, Church GM, Collins JJ, Irion S, Daley GQ. “Reprogramming of T cells from human peripheral blood”; Cell Stem Cell (2010), 7:15-19. PMID: 20621044.

Urbach A#, Bar-Nur O# , Daley GQ*, Benvenisty N*. “Differential modeling of fragile X syndrome by human embryonic stem cells and induced-pluripotent stem cells” Cell Stem Cell (2010), 6:407-411. PMID: 20452313. # These authors contributed equally to this work. * co-correspondence authors

Loh YH, Agarwal S, Park IH, Urbach A, Huo H, Heffner GC, Kim K, Miller JD, Ng K, Daley GQ. “Generation of induced pluripotent stem cells from human blood“ ; Blood (2009) 113: 5476-5479. PMID: 19299331.

Urbach A, Benvenisty N. “Studying early lethality of 45,XO (Turner’s syndrome) embryos using human embryonic stem cells”; PLoS ONE (2009); 4:e4175. PMID: 19137066.

Eiges R#, Urbach A#, Malcov M, Frumkin T, Schwartz T, Eden A, Amit A, Benvenisty , Ben-Yosef D. “Developmental study of fragile X syndrome using human embryonic stem cells derived from preimplantation genetically diagnosed embryos”; Cell Stem Cell (2007) 1:568-577. PMID: 18371394 # These authors contributed equally to this work

Urbach A, Schuldiner M, Benvenisty N. “Modeling for a human disease by gene targeting in human embryonic stem cells”; Stem Cells (2004) 22:635-641. PMID: 15277709.